GRACE ACS Mortality Score
Enter clinical and laboratory variables collected on admission to calculate the GRACE score and stratify 6-month mortality risk.
How to Use This Calculator
Collect admission data
Use initial vitals, labs, Killip class, ECG findings, and history at presentation for acute coronary syndrome.
Enter values carefully
Ensure units are correct (mg/dL for creatinine) and record whether biomarkers and ST segments are abnormal.
Apply guideline recommendations
High-risk patients typically benefit from early invasive evaluation and intensive secondary prevention.
Formula
The GRACE score is derived from weighted coefficients applied to age, heart rate, systolic blood pressure, creatinine, Killip class, cardiac arrest, ST deviation, and cardiac biomarkers. The points table above reproduces the validated GRACE 6-month mortality score categories.
Full Description
The GRACE (Global Registry of Acute Coronary Events) score stratifies mortality risk in acute coronary syndrome. Scores <109 indicate low risk, 109–140 intermediate risk, and >140 high risk. It informs timing of invasive angiography, intensity of antithrombotic therapy, and disposition decisions. Updated models (GRACE 2.0) incorporate more variables, but the original score remains widely used clinically.
Frequently Asked Questions
Can troponin-negative patients still have elevated risk?
Yes. Even without biomarker elevation, age, hypotension, or heart failure can push scores to intermediate/high categories.
How does GRACE compare with TIMI?
GRACE provides continuous risk estimates and often outperforms TIMI risk scores in discrimination for mortality.
Should I use GRACE 2.0 instead?
GRACE 2.0 offers updated coefficients, but classic GRACE remains guideline-endorsed and easy to implement at bedside.
Does renal replacement therapy change creatinine input?
Use the most recent serum creatinine prior to dialysis initiation. Consider chronic kidney disease as a major risk enhancer.