Aleve Dosage Guidance
Calculate weight-based dosing for pediatric use or review adult OTC limits, including dosing frequency and maximum daily amounts.
Common: every 8–12 hours.
Dosing Recommendation
Per dose
220 mg
Every 12 hours (≤ 2 doses/day).
Daily maximum
660 mg/day
OTC maximum is 660 mg/day. Prescription maximum: 1500 mg/day.
How to Use This Calculator
Choose the correct age group
Aleve is OTC for ≥12 years; pediatric dosing is off-label and typically specialist-directed.
Enter weight and interval
Weight-based dosing applies to pediatrics; adults generally use fixed 220 mg doses.
Review safety limits
Limit to ≤5 days for pain or ≤3 days for fever unless directed by a clinician.
Formula
Pediatric per dose (mg) = weight (kg) × 5 mg/kg (max 250 mg).
Based on FDA OTC labeling and pediatric rheumatology dosing references.
Frequently Asked Questions
Can Aleve be combined with other NSAIDs?
No. Avoid concurrent NSAIDs (e.g., ibuprofen) to reduce GI and renal toxicity.
Is naproxen safe in pregnancy?
Avoid in the third trimester. Use with caution in the first and second trimesters only if benefits outweigh risks.
What renal/hepatic adjustments are needed?
Dose reduction or avoidance is recommended in significant renal impairment or advanced liver disease.
How quickly does Aleve work?
Onset 30–60 minutes; peak at 2–4 hours. Duration up to 12 hours.
What if pain persists?
Seek medical evaluation if pain lasts >5 days (adults) or >3 days (children) or worsens.