Gabapentin Dosing Planner

Calculate per-dose amounts, titration schedules, and renal dosing for gabapentin based on indication and creatinine clearance.

Typical effective range: 900–3600 mg/day.

Common: 3 times daily (TID). Twice daily for lower renal function.

Use Cockcroft-Gault or measured renal function.

Per-dose calculation

Per dose

600 mg

1800 mg/day divided into 3 doses.

Renal adjustment

CrCl 80 mL/min → 300 mg three times daily (start 300 mg nightly, titrate to 900–3600 mg/day)

Titrate gradually to minimize dizziness and somnolence. For elderly patients or renal impairment, use the renal dosing recommendation over weight-based titration.

Suggested titration

Day 1: 300 mg at bedtime

Day 2: 300 mg twice daily

Day 3: 300 mg three times daily

Increase by 300 mg/day every 2–3 days as needed (max 3600 mg/day)

How to Use This Calculator

1

Select indication

Different conditions have distinct titration schedules. Choose the one prescribed.

2

Enter desired maintenance dose

Use prescriber’s target or typical therapeutic dose (e.g., 1800 mg/day for pain).

3

Adjust for renal function

Override daily dose if renal function requires lower dosing frequency or amount.

Formula

Per dose (mg) = Total daily dose ÷ doses per day.

Sources: Gabapentin prescribing information, AAN neuropathic pain guidelines, renal dosing references.

Frequently Asked Questions

How fast can I titrate?

Increase no faster than every 2–3 days to limit CNS adverse effects.

Is there a loading dose?

Typically no; start low and titrate unless treating acute severe pain with specialist guidance.

What about extended-release formulations?

Horizant® and Gralise® have different dosing; use product-specific calculators.

Can I split the daily dose unevenly?

Yes—larger evening doses can reduce daytime somnolence (e.g., 300-300-600 mg). Document clearly.

What if doses are missed?

Take as soon as remembered unless close to next dose; never double dose.