Daily Opioid MME
Enter an opioid, route, and total daily dose to calculate the morphine milligram equivalent (MME). MME helps contextualize overdose risk and compare regimens.
Result
Morphine milligram equivalent
60.0 MME/day
40.00 mg/day × conversion factor 1.5.
How to Use This Calculator
Determine total daily opioid dose
Add all doses for the day, including ER/IR formulations. Convert per-dose amounts to daily totals.
Select opioid and route
MME factors differ by medication and route (oral vs parenteral vs transdermal). Pick the appropriate combination.
Interpret MME total
Use the MME to flag high-risk regimens, compare alternative therapies, and document justification in clinical notes.
Formula
MME/day = Daily opioid dose × Conversion factor.
Conversion factors sourced from CDC guidelines (2016, updated 2022) and state prescription monitoring program references.
Frequently Asked Questions
Do I add MMEs for multiple opioids?
Yes. Calculate each opioid’s MME and sum them to obtain the patient’s total daily MME.
Why is methadone complicated?
Methadone potency increases with dose and chronic use. Apply clinical judgement and consult specialty references for high doses.
Is MME the same as equianalgesic conversion?
MME standardizes potency to morphine for overdose risk assessment. Equianalgesic conversions may involve additional adjustments (e.g., cross-tolerance reduction).
Can I use this for pediatric patients?
No. Pediatric opioid dosing requires specialized references; MME thresholds differ.
What about short-acting PRN doses?
Include the expected daily amount. If PRN usage varies, document assumptions or provide a range of possible MME totals.