Neutrophil-to-Lymphocyte Ratio

Input neutrophil and lymphocyte measurements to assess the inflammatory NLR marker. Choose whether values represent absolute counts (×10⁹/L) or differential percentages.

NLR

2.33

NLR 2–3 is within the typical reference range for healthy adults.

How to Use This Calculator

1

Obtain differential counts

Use a complete blood count with differential to acquire neutrophil and lymphocyte counts (absolute or percentages).

2

Select units and enter values

Choose absolute counts or percentages. If using percentages, provide total WBC to convert.

3

Interpret the NLR

Relate the NLR to clinical context— elevated values often correlate with systemic inflammation, infection, or malignancy prognosis.

Formula

NLR = Neutrophil count ÷ Lymphocyte count

Counts may be absolute (×10⁹/L) or converted from differential percentages using total WBC.

Full Description

Neutrophil-to-lymphocyte ratio is a widely studied biomarker reflecting systemic inflammation and stress. Elevated NLR correlates with adverse outcomes in cardiovascular disease, sepsis, and numerous cancers, while low ratios are typical in healthy individuals. NLR should complement, not replace, thorough clinical evaluation and other laboratory markers such as CRP, ferritin, and procalcitonin.

Frequently Asked Questions

Can medications affect NLR?

Yes. Steroids, chemotherapy, and immunosuppressants can alter neutrophil and lymphocyte counts, impacting NLR.

What is a normal NLR?

Values between 1 and 3 are generally considered normal in adults, but reference ranges vary with population and lab methods.

Should NLR be used for screening?

No. Use NLR as an adjunctive marker within a broader clinical and laboratory assessment.

Do I need WBC for absolute counts?

If you already have absolute neutrophil and lymphocyte counts, WBC is not required. It’s only needed when starting from percentages.